pi3kγ (p110γ Search Results


pi3kγ p110γ assay kit  (BPS Bioscience)
93
BPS Bioscience pi3kγ p110γ assay kit
Baicalein is a potential inhibitor of <t>PI3Kγ.</t> (A) pharmacological network of baicalein (molecular ID: mol002714) and melanoma targets generated with Cytoscape V3.8.1. The property of yellow nodes are the common targets of drug and disease. All protein targets are represented by their gene symbols. (B) , protein-protein interaction (PPI) network of drug and disease target analysis. (C,D) the mRNA expression and protein levels of PI3Kγ p110 in THP-1-derived M1 macrophages with or without baicalein treatment. (E) the molecular docking of baicalein on PI3Kγ. (F) the binding curve of baicalein to PI3Kγ was measured by SPR. (G) the inhibitory effect of baicalein on PI3Kγ. Data are presented as mean ± SD and are obtained from at least independent experiments. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001, for comparison with control group. BA = baicalein.
Pi3kγ P110γ Assay Kit, supplied by BPS Bioscience, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 93 stars, based on 1 article reviews
pi3kγ p110γ assay kit - by Bioz Stars, 2026-03
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Baicalein is a potential inhibitor of PI3Kγ. (A) pharmacological network of baicalein (molecular ID: mol002714) and melanoma targets generated with Cytoscape V3.8.1. The property of yellow nodes are the common targets of drug and disease. All protein targets are represented by their gene symbols. (B) , protein-protein interaction (PPI) network of drug and disease target analysis. (C,D) the mRNA expression and protein levels of PI3Kγ p110 in THP-1-derived M1 macrophages with or without baicalein treatment. (E) the molecular docking of baicalein on PI3Kγ. (F) the binding curve of baicalein to PI3Kγ was measured by SPR. (G) the inhibitory effect of baicalein on PI3Kγ. Data are presented as mean ± SD and are obtained from at least independent experiments. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001, for comparison with control group. BA = baicalein.

Journal: Frontiers in Pharmacology

Article Title: Baicalein Potentiated M1 Macrophage Polarization in Cancer Through Targeting PI3Kγ/ NF-κB Signaling

doi: 10.3389/fphar.2021.743837

Figure Lengend Snippet: Baicalein is a potential inhibitor of PI3Kγ. (A) pharmacological network of baicalein (molecular ID: mol002714) and melanoma targets generated with Cytoscape V3.8.1. The property of yellow nodes are the common targets of drug and disease. All protein targets are represented by their gene symbols. (B) , protein-protein interaction (PPI) network of drug and disease target analysis. (C,D) the mRNA expression and protein levels of PI3Kγ p110 in THP-1-derived M1 macrophages with or without baicalein treatment. (E) the molecular docking of baicalein on PI3Kγ. (F) the binding curve of baicalein to PI3Kγ was measured by SPR. (G) the inhibitory effect of baicalein on PI3Kγ. Data are presented as mean ± SD and are obtained from at least independent experiments. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001, for comparison with control group. BA = baicalein.

Article Snippet: For the measurement of the kinase activity of PI3Kγ, ADP-Glo kinase assay kit (Promega, Madison, WI, United States, Cat#V910) and PI3Kγ (p110γ) assay kit (BPS Bioscience, San Diego, CA, Cat#79803) were used.

Techniques: Generated, Expressing, Derivative Assay, Binding Assay